Keywords to use administration information

Doses from the design can also be referenced through several matching independent variables. This allows for some direct calculation, especially for modelling custom single dose absorptions. Doses aren’t discriminated according to their administration types here. These values are directly related to the design, they are unaffected by the PK elements.

Time of the last administered dose

The keyword tDose defines the time of the last administered dose. This is a step function. Its value is unaffected by any lag time Tlag. Indeed, a lag time targets the dose absorption. tDose is null before the first dose.

Amount of the last administered dose

The keyword amtDose defines the amount of the last administered dose. This is a step function. Its value is unaffected by any proportional factor p, as this keyword targets the absorbed amount by the end of the whole absorption process. amtDose is null before the first dose.

Infusion time of the last administered dose

The keyword inftDose defines the infusion time of the last administered dose. This is a step function. Its value is unaffected by any proportional factor p, as this keyword targets the absorbed amount by the end of the whole absorption process. The rate of the final absorption can be different from the rate of the administration process. inftDose is null before the first dose.