Lixoft is providing model libraries to simplify the use of its software. The mathematical expressions of the pharmacokinetic and pharmacodynamic models implemented in MonolixSuite can be found here: PKPDlibrary
Pharmacokinetic models
The equations in the ensuring chapter describe the pharmacokinetic models implemented in the MonolixSuite software. The presentation of the models is organised as follows:

 First level: number of compartment
 One compartment
 Two compartments
 Three compartments
 Second level: route of administration
 IV bolus
 Infusion
 First order absorption
 Zero order absorption
 Third level: elimination process
 Linear
 MichaelisMenten
 Fourth level: existence of a lag time for first and zero order absorption only
 First level: number of compartment
The equations express the concentration C (t) in the central compartment at a time t after the last drug administration.

 Single dose: at time t after dose D given at time
 Multiples doses: at time t after n doses for i from 1 to n given at time
 Steady state: at a time t after dose D given at time after repeated administration of dose D given at interval (only for linear elimination)
Pharmacodynamic models
Many pharmacodynamical models are also proposed with MonolixSuite software. Some of these pharmacodynamic models can be used alone or linked to any pharmacokinetic model. Some can only be used linked to a pharmacokinetic model. The two main type of models are:
 The immediate response models (alone or linked to a pharmacokinetic model). An example can be seen here.
 The turnover models (only linked to a pharmacokinetic model). Examples can be seen here.
Any combination drug action models and baseline/disease models is available are also available.